The mechanism of skin ageing
The process of skin ageing is complex and influenced by a myriad of intrinsic and extrinsic factors. The most prominent intrinsic biological processes involved in skin ageing are alterations in DNA repair and stability, mitochondrial function and cellular metabolism. Extrinsic factors such as UV radiation and free radical damage cause morphological alterations in the dermis, alter fibroblast activity and, ultimately, lead to a thinner epidermis, loss of collagen and weakened skin repair.
Over time, the loss of structural proteins collagen and elastin impact skin’s ability to maintain its shape and structural integrity. Unable to withstand mechanical shocks and environmental stressors, the epidermis slackens, collapses and loses its defined shape.
The Solution
[video width="1080" height="1080" mp4="https://zo-skinhealth.co.uk/wp-content/uploads/2020/06/01-10.mp4"][/video]Firming Serum’s bioactive formula supports the anchoring fibrils that connect the dermis to the epidermis and maintains the structural integrity of the skin.
Sodium DNA
Fibroblast cells in ageing skin become inactive and unable to restore collagen and elastin. Sodium DNA works alongside skin’s matrix formation process to support fibroblast activity and improve elasticity and firmness.ZCORE Anti-Inflammatory Complex
Fibrillar degeneration weakens the dermal-epidermal junction and results in inadequate nutrient replenishment between the dermis and the epidermis. ZCORE complex features biomimetric tetrapeptide and sweet yellow clover to support the anchoring fibrils for dermal-epidermal junction integrity.Clinically Proven Results
In a comprehensive clinical study of 45 participants, Firming Serum has been proven to improve the appearance of firmness, sagging and help maintain skin’s shape and strength.97% of participants showed significant improvement in firmness by week 12 as measured by Cutometer, 88% demonstrated elasticity improvement while 93% of subjects showed significant improvement in mid-face and jawline sagging by week 12 measured by an expert clinical grader.