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ZO Skin Health Firming Serum – Defying the Mechanism of Skin Ageing

Formulated with an exclusive biomimetric complex and anti-inflammatory system, ZO Skin Health Firming Serum reduces the appearance of sagging and skin laxity for a more defined facial contour.

The mechanism of skin ageing

The process of skin ageing is complex and influenced by a myriad of intrinsic and extrinsic factors. The most prominent intrinsic biological processes involved in skin ageing are alterations in DNA repair and stability, mitochondrial function and cellular metabolism. Extrinsic factors such as UV radiation and free radical damage cause morphological alterations in the dermis, alter fibroblast activity and, ultimately, lead to a thinner epidermis, loss of collagen and weakened skin repair.

Over time, the loss of structural proteins collagen and elastin impact skin’s ability to maintain its shape and structural integrity. Unable to withstand mechanical shocks and environmental stressors, the epidermis slackens, collapses and loses its defined shape.

The Solution

Firming Serum’s bioactive formula supports the anchoring fibrils that connect the dermis to the epidermis and maintains the structural integrity of the skin.

Sodium DNA

Fibroblast cells in ageing skin become inactive and unable to restore collagen and elastin. Sodium DNA works alongside skin’s matrix formation process to support fibroblast activity and improve elasticity and firmness.

ZCORE Anti-Inflammatory Complex

Fibrillar degeneration weakens the dermal-epidermal junction and results in inadequate nutrient replenishment between the dermis and the epidermis. ZCORE complex features biomimetric tetrapeptide and sweet yellow clover to support the anchoring fibrils for dermal-epidermal junction integrity.

Clinically Proven Results

In a comprehensive clinical study of 45 participants, Firming Serum has been proven to improve the appearance of firmness, sagging and help maintain skin’s shape and strength.

97% of participants showed significant improvement in firmness by week 12 as measured by Cutometer, 88% demonstrated elasticity improvement while 93% of subjects showed significant improvement in mid-face and jawline sagging by week 12 measured by an expert clinical grader.

Comprehensive Solutions

Targeted treatment of laxity and sagging cannot replace the basics steps of a healthy routine – cleanse, exfoliation, UV and antioxidant protection. Firming Serum’s lightweight formula is mild enough to be tolerated by all skin types and suitable for sensitive skin areas. It can, therefore, be added to all anti-ageing programmes. Firming Serum is applied AM and PM after GSR and Daily Power Defense and before high molecular weight products such as Growth Factor Serum.

 

 

ZO Skin Health Wrinkle + Texture Repair – New, Improved Formula

ZO Skin Health’s comprehensive anti-ageing solution has been reformulated to increase efficacy and accelerate treatment results.Beneath the surface, the first manifestation of skin ageing begins with the degradation of skin’s collagen network.

Wrinkle + Texture Repair targets the underlying pathophysiology of skin ageing and stimulates the restoration of collagen-1, fibronectin and hyaluronic acid aids in skin’s collagen network. The formula features a blend of retinol, carprooyl tetrapeptide-3, melilotus officinalis extract, Buddleja davidii meristem cell culture and phospholipids that work synergistically to restore natural hydration and minimise the appearance of wrinkles and all signs of ageing.

zo skin health wrinkle + texture repair

Advanced Delivery System

The key to Wrinkle +Texture Repair lies efficacy in its new delivery system. ZO Skin Health has introduced a microemulsion delivery system that enables the rapid release of retinol and accelerated penetration in the deeper skin layers.

Clinically Proven Results

  • The Study

A 12-week clinical study, including 43 subjects was conducted to evaluate the effect of Wrinkle + Texture Repair formula on the facial skin of female subjects.

All subjects were initially analysed at baseline, and then reassessed at 2, 4, 8, and 12 weeks of product use. Skin changes in all subjects were analysed by an external grader, utilising a visual scale to measure lines, wrinkles and changes in skin texture.

Bio-instrumental analyses were also conducted utilising Tewameter to assess trans-epidermal water loss and digital images were obtained with a Clarity 2D system at all study timepoints, and analysed by a trained technician. All data points were compared against baseline visit results.

  • The Results

After 12 weeks of application, a significant improvement in all expert graded skin attributes was found, and no significant adverse events were reported during the study. Participants were overwhelmingly satisfied with the results, with 93% of participants showing improvement by the end of the study. 98% of participants showed improvements in crow’s feet and facial fine lines by week 12, and 95% of participants showed improvements in skin function by week 12.

Furthermore, none of the expert graded results showed any plateauing effect at the conclusion of the study, which suggests that patients may expect to see even further benefits when using the product for longer than 12 weeks.

Growth Factors: Do They Work & How to Iclude Them in Your Routine

 

Looking for the perfect anti-ageing ingredient? Ask any skin expert for the ingredient they swear by and you will hear at least two of the following: sunscreen, retinol, antioxidants, hyaluronic acid, peptides. These are the ultimate wrinkle-fighters and radiance warriors that any skincare lover keeps in their stash. But there’s a new complexion mandate that has quietly entered the fold: growth factors.

Here’s everything you need to know about how they work and how to incorporate a growth factor serum in your routine:

What are growth factors?

Growth factors are groups of proteins that occur naturally in our bodies. They’re produced by all types of cells and are responsible for the regulation of vital cellular functions, such as survival, proliferation, migration and differentiation. Simply put, growth factors can command your cells to replicate, repair and rejuvenate.

How growth factors benefit the skin?

When it comes to fighting skin ageing, growth factors are the true all-rounders.

By our late 20s the natural production of growth factors in the skin starts to decline which lays the groundwork for wrinkles, sagging and skin thinning. Adding them topically through your skincare will stimulate the production of fibrous proteins such as collagen and elastin to improve skin thickness and texture. Boosting collagen production also enhances the skin’s natural ability to heal and hydrate.

Do they really work?

In a word? Yes. In our most recent study 92% of participants noticed significant improvement in fines and crow’s feet after following the simple routine of cleansing, applying Growth Factor Serum and wearing SPF every day for 12 weeks. Furthermore, clinicians observed 31% improvement of skin thickness after just 4 weeks of using Growth Factor Serum in the morning and evening and PM and the number continued to increase throughout the completion of the study.

Overall, 95% of participants reported visible improvement in their skin texture and smoothness, 92% reported overall improvement in all signs of ageing and 78% said their skin felt tighter and firmer.

How can I incorporate them in my skincare routine?

While growth factors are one of the best active ingredients for skin rejuvenation, they can’t replace the basics of your routine – sun protection, exfoliants and antioxidants. Think of them as the icing on the cake that can bolster your existing skincare regime and slow down the ageing process with much less irritation than other gold-standard ingredients such as retinol.

4 Signs You Are Over-Exfoliating Your Skin

over-exfoliating, signs of over-exfoliation

There’s no denying exfoliation is a wonderful thing for your skin. A good scrubbing session takes off dirt and excess oils, boosts circulation and leaves your face smooth and silky. But too much of a wonderful thing can be a bad thing. Over-exfoliating is the one skincare mistake almost all of us make. While we scrub and peel our faces in an attempt to keep our skin happy and healthy, too much of it is doing more harm than good. Here are the 5 signs of over-exfoliation to watch out for:

#1. Your face is too shiny

If your face shines like a disco ball, you need to give it a break from exfoliators. Light reflects off over-exfoliated skin easily, because its natural texture has been overly smoothed (yes, there is such a thing as too much smoothness).

#2. Your breakouts are getting worse

Excessive exfoliation strips your skin from its natural moisture which prompts your sebaceous glands to produce more oil to compensate for the loss of hydration. In addition, scrubbing too aggressively too often can disrupt skin’s lipid barrier and hinders its ability to protect the under-layers from bacteria and free radicals.

#3. Your skin feels like it was sunburned

Redness, itchiness, and puffiness are all inflammatory responses, signalling that your skin is in distress. The top layer of your epidermis acts like a shield against allergens, irritants and pollutants. When this natural exterior barrier is compromised, your skin becomes more susceptible to irritants and environmental damage.

#4 Your skin feels like crepe paper

When you are over-exfoliating, you are scrubbing away healthy skin cells and lipids that help your skin retain its natural hydration levels. If your skin feels flaky and fine lines suddenly become more visible, that’s a sure sign your skin doesn’t retain sufficient moisture.

ZO® Signature Peels: Retinol Stimulation Peel

The ZO® Retinol Stimulation Peel is ideal for skin that has a rough texture, uneven tone, dullness and lines and wrinkles.

retinol stimulation peel

Key Features of the ZO® Retinol Stimulation Peel

  • A physician-directed, at-home peel that utilises Ossential® Advanced Radical Night Repair for epidermal renewal and dermal stimulation.
  • High potency 1.0% retinol encapsulated in time-released microspheres that penetrate the epidermis and deliver maximum efficacy with minimal irritation.
  • Provides superficial exfoliation, promotes cell turnover and stimulates deeper cellular activity for firmer more even toned skin.
  • Improves the appearance of the skin and also its ability to repair and renew itself.
  • Highly tolerable with no downtime.
  • Ideal for the face, neck, and chest.
  • Has potent antioxidant, anti-redness and anti-irritation effects.
  • Stabilises the epidermis and skin barrier function.

Benefits of This Peel

  • Repairs damaged surface skin
  • Strengthens skin and reduces sensitivity
  • Improves skin texture
  • Tightens large pores
  • Reduces and corrects abnormal surface pigmentation and sun damage
  • Minimises the appearance of fine lines
  • Brightens, smooths and tightens skin for a more youthful appearance

ossential-advanced-radical-night-repair

Your At-Home Step

The Ossential® Advanced Radical Night Repair is a key at-home step for the ZO Retinol Stimulation Peel. But what are its benefits for the skin?

  • It has the highest concentration of retinol in an over-the-counter product retinol
  • It stimulates epidermal renewal and collagen production and helps even skin tone
  • Contains vitamins A, C, and E to provide powerful antioxidant protection, preventing future skin ageing
  • This anti-ageing serum also suppresses irritation and redness to restore a more youthful skin tone
  • But it doesn’t stop there, this incredible serum also hydrates and restores the skin barrier with essential lipids to reverse dry, dull skin

The importance of sun protection – Fiona Collins

Interview with Fiona Collins, Fiona And Marie Aesthetics, about the importance of sun protection.

Under the Skin is a one-to-one interview that addresses different skin issues and concerns, providing the latest information about ZO Skin Health protocols and treatments for the consumer clients.