Want to know why you should try ZO Skin Health products? These blog posts will tackle several skin health myths + how our products affect your skin health

Target inflammaging with the reformulated ZO Skin Health Daily Power Defense

Inflammation has become a big focus in the skincare arena and for good reason. Yes, it’s a much-needed immune response that signals the body to heal and repair damaged tissue and defend against invaders like viruses and bacteria. But in excess, inflammation does more harm than good.

Chronic inflammation caused by sun, pollution, smoke and chemical exposure, alongside internal stressors like poor diet, lack of sleep and mental stress, all contribute to leaving the body in a constant state of inflammation – cue inflammaging.

zo skin health daily power defense

It’s an emerging area of science and research – but what we do know is that the accumulation of free radical damage caused by extrinsic and intrinsic factors leaves the skin unable to repair as well as it should. This leads to chronic skin conditions that exhaust the skins defensive and regenerative capacity, resulting in inflammaging,” explains Rick Woodin, Chief Scientist at ZO Skin Health.

The likes of acne, eczema and psoriasis are well known inflammatory conditions, but inflammaging is a little more covert and undetectable – at least at first. “It’s a low-grade asymptomatic condition, so you don’t see a lot of redness,” shares Woodin. What you will see though over time is dehydration, sagging, uneven skin tone, and lines and wrinkles. This is because inflammaging impairs the protective barrier function, triggers pigmentation and leads to a loss of collagen, elastin, and hyaluronic acid.

Through research we also learnt that the skin contains inflammasomes. These are immune system receptors and sensors that regulate the activation of caspase-1 and induce inflammation that’s been implicated in a host of inflammatory disorders,” adds Woodin.

The science behind Daily Power Defense


Rather than shut down these inflammasomes, the aim is to stop them from becoming hyperactive – which is triggered when increased amounts of oxidants exceed the skin’s antioxidant defence system capacity. ZO Skin Health response to this, is the new supped up Daily Power Defense.

Clinically studies show that thanks to advanced ZO technologies, namely the ZPOLY™ complex – this serum’s new formula it is able to offer a significant improvement in skin hydration, uniformity, radiance, and the depth of lines and wrinkles.

Exclusive to ZO, the ZPOLY™ complex is a plant-derived polysaccharide complex of brown seaweed extract, prickly pear stem cell extract, mushroom, and larch tree that provides powerful prevention by minimising the expression of Caspase 1, a key protein responsible for inflammaging. It also accelerates barrier repair to fortify skin against future external and internal stressors that cause premature aging. As well as boosts hydration after a single application to immediately revive dehydrated and dull skin.

And it doesn’t end there, Vitamins A and E plus ZO-RRS2® – a combination of edelweiss, white horehound and meristem cell cultures – provide powerful antioxidant protection, neutralising oxidative stress and minimizing inflammation to prevent future skin damage. While enzyme extracts Micrococcus lysate, and arabidopsis thaliana enhance and shorten natural cellular repair to ensure optimum skin health, and an Omega-6 ceramide replenishes lipids and helps restore skin barrier function.

Made to be used both morning and night, this light serum that’s suitable for all skin types and tones is a major game changer in the fight against inflammaging – you heard it here first!

ZO Ambassadors at West Ham United Women Talk About Their ZO Journey to Healthy Skin

west ham united women

The Wigmore Medical team visited West Ham’s Chadwell Heath Training Ground to catch up with ZO Skin Health Ambassadors Grace Fisk, Maisy Barker, and Kateřina Svitková and learn more about their journey to healthy skin. The ambassadors have been following a ZO Skin Health regime, prescribed and tailored to their individual needs and skin concerns by Dr Raul Cetto, the team’s official Skin Consultant. Here is what the players had to share with us:

How has your new ZO skincare regime changed your attitude to skincare?

Grace: ZO has really helped me and taught me a lot of things about my skin which I didn’t know before. Dr Raul has been really helpful, teaching me what’s good and what’s bad for my skin.

Maisy: Seeing the improvement of my skin since using ZO has really motivated me to stick to my routine. If you stick to it, the products will work. It has pushed me to look after my skin a bit more and understand what I need to do to make sure my it is where I want it to be.

Kateřina: I feel the regime is much healthier. After the team showed me what my face would like when I’m 80, I just started putting more thought into what goes on my face every day.*

How did you previously look after your skin – what did you use?

Grace: I went through a lot of over-the-counter products. I didn’t really know what and when to use, what kind of products or active ingredients. ZO have been really helpful for me, they have medical science behind their products, so they are safe for me to use and have the right ingredients that help my skin and not harm it. It’s a big difference from what I was using before.

Maisy: I just used basic products, because I didn’t understand my skin that thoroughly. So, I’ve been speaking to the team at ZO to understand what I need for my skin, the products at ZO are so individual, I think that helps a lot.

Kateřina: would normally wash my face and that was all I did.

How does the regime fit into your lifestyle?

Grace: My new regime is quite intense – it’s an morning and evening routine. It takes commitment but ZO have made it really easy for me. It’s a step by step routine, I know when to use each product and it is a lot easier to follow.

Maisy: I’ve been using the products for about eight months, so I’m used to applying them morning and evening. It’s part of my morning routine now and it gets me ready for the day.

Kateřina: I like that it is a morning and evening routine, it doesn’t take too much time, it’s really easy to follow.

What’s the most useful thing you’ve learned since starting the regime?

Grace: The most useful thing is probably protection from the sun; making sure that I apply SPF protection even if it’s not sunny outside. The sun can harm your skin even through clouds and you don’t that long-term.

Maisy: Understanding that everyone’s skin is different and being patient with the products because they will work. But everyone reacts differently to products, so just being patient and working with the ZO team to make sure I get what’s right for my skin. Ultimately, what works for me might not work for someone else.

Kateřina: Before I got to learn about ZO Skin Health products, I didn’t really know I should care a bit more about my skin. Especially with sunscreen, I wasn’t aware that even if don’t get a sunburn, my skin can still get damaged. I

*All ZO Skin Health Ambassadors had a VISIA scan as part of their first skin consultation.

We Are Proud to Support West Ham United Women as Official Sponsors

We believe that when you feel confident in your skin, you perform at your best. Here at ZO Skin Health UK, we have always been committed to skincare innovation and developing comprehensive solutions that enable patients to feel comfortable and confident in their skin – no matter their age or skin type.

We are proud to support the West Ham United women’s team as an official sponsor and skincare partner, giving them the confidence to feel and play at their best.

west ham united woman

“It is a pleasure to welcome ZO Skin Health to West Ham United as the newest partner of our women’s team. ZO Skin Health has a proven reputation of being both a pioneering business in skin therapy technologies and a comprehensive educator of best skincare practice for both physicians and patients.

Furthermore, ZO Skin Health have displayed a genuine passion for encouraging growth in women’s football. ZO Skin Health are committed to providing the best skincare solutions for all skin types to enable girls and women alike to have complete confidence. I believe this to be the start of a long, successful partnership between ourselves and ZO Skin Health” – Jack Sullivan, West Ham United women’s Managing Director.

West Ham United Women

“We are delighted to be working with West Ham women’s team on this sponsorship deal. We know that skin confidence affects everyone, so no matter what their job and lifestyle, everyone deserves to feel their best. We hope by partnering with West Ham women’s team we can help each of the players feel and play their best!” – Raffi Eghiayan, ZO Skin Health Product Development, and Marketing Director

For more news on this exciting new partnership, follow our Instagram and Facebook page and tune into West Ham United women’s official page.


Four Players from West Ham United Women Named ZO Skin Health Ambassadors

west ham united women zo ambassadors

Four West Ham United women’s team players have been named ambassadors for ZO Skin Health UK in a new initiative, aiming to promote good skin health habits.

ZO became the team’s official skincare partner and sponsor in 2019 and has since supported the players with expert skin health advice and tailored skincare regimes to give them the confidence to feel and play at their best. The new ambassadors, Grace Fisk, Katerina Svitkova, Maisy Barker, and Yui Hasegawa had their consultation with Dr Raul Cetto at Chadwell Heath training ground.

I enjoy working with the players and most importantly being able to educate them in preventing and reversing skin damage. They are high-performance athletes and skin is the largest organ in our body. It’s important that players look after it in the same way they look after their joints and diet”, said Dr Cetto who was appointed as the team’s first ever skin consultant back in 2019.

Using state-of-the-art scanning technology, ZO Skin Health team were able to examine the players skin in extreme detail and unveil signs of damage that are not yet visible to the naked eye. “We can identify the early signs of damage and reverse them with ZO Skin Health products that work at the cellular level”, explained Dr Cetto.

Football players experience all different types of weather conditions during the course of a season, their skin is exposed to harsh weather, air pollution, and UV rays. This is why antioxidants are a vital part of the players’ skincare regimes. ZO’s exclusive slow-release antioxidant complex is designed to combat oxidative stress and prevent free radical damage and strengthen the protective barrier function.

During the consultation, the four players shared that despite spending hours on the training ground every day, they often forget to apply SPF protection. While for many people sunscreen is synonymous with summer holidays and pool days, according to Dr Cetto, UV radiation is the number one aggressor to the skin and responsible for the majority of the visible signs of ageing.

Long-wavelength UVA rays are present year-round, they can penetrate the deeper layers of the skin and pass through clouds and glass. This is why Dr Cetto recommended ZO Skin Health’s Sunscreen + Powder SPF 30 as the last step in the ambassadors’ regimes. The powder is formulated with zinc oxide and titanium dioxide to offer a physical protection against UVA and UVB rays, while the ZOX12® complex protects against free radical damage and and IR-A rays. Fractioned melanin protects against blue (HEV) light and gives a light buildable coverage. The compact brush format makes it easy and convenient to reapply sun protection throughout the day.

Hopefully, the players will be our future advocates for skin health. We want to create awareness especially amongst young people so that they know how to prevent skin damage and embrace good skin health habits which can be as simple as washing your face and applying sun protection regularly”, added Dr Cetto.

We will be keeping track on the progress of the players over the coming months, so make sure to follow ZO Skin Health UK on our Instagram and Facebook channels to never miss an update!

Introducing ZO Skin Health Growth Factor Eye Serum

Whether it’s wrinkles, hollowness, discolouration or puffiness, the skin around the eyes shows signs of ageing before any other part of the body. There is a common misconception that the products you use on the rest of the face will work just fine on the delicate eye area too. Unfortunately, this is not the case. The skin around the eyes is fragile and especially vulnerable to external aggressors like UV exposure and pollution. To repair damage and slow down the ageing process, you need a powerful, targetted treatment.

What makes the eyes more vulnerable to both intrinsic and extrinsic factors of ageing?

  • The skin is very thin and has a sparse fat layer – because of that, collagen and elastin (the proteins that give skin strength and firmness) are more prone to degradation caused by sun and pollution exposure.

  • Muscular subsidence and microcirculation decline – the muscles that squeeze the eyelids shut decrease in strength with age and that leads to sagging and deep creases.

  • Anatomical peculiarity – the skin around the eyes covers the hollow space of the eye socket. As we age, the bony orbit of the eye changes in structure; the skin caves in, giving the eyes a sunken and darkened appearance.

The Solution

Powered by ZO Skin Health innovative skin restoration technology, Growth Factor Eye Serum targets the appearance of deep eye wrinkles, crease formation, hollowness and microcirculation decline.

The formula combines enzymatic and plant-derived growth factors that invigorate skin’s natural restorative mechanisms and deliver targetted treatment for the eye’s unique vulnerabilities.

growth factor eye serum

Key Ingredients:

Neuropeptide – improves the appearance of expression lines and smooths out wrinkles.

Sodium Acetylated Hyaluronate – provides an instant boost in hydration and plumpness.

Growth factors – stimulate the production of type 1 collagen, increase fibroblast division and enhance skin density.

ZPRO antioxidant complex – increases hyaluronan contents in the skin which, in return, boosts collagen and hyaluronic acid production.

Growth Factor Eye Serum is suitable for all skin types and can be added to your skincare regime morning or evening as a targeted eye treatment.

The formula offers a unique blend of fast-acting and long-term correction ingredients; neuropeptides and sodium hyaluronate provide instant hydration boost and smooth out fine lines, while growth factors and antioxidants work within the deep layers of the skin to improve density and stimulate collagen production. It comes with a cooling applicator that makes it easy to apply just the right amount of product and can be used to alleviate swelling and puffiness.

Growth Factor Eye Serum is available to purchase form your nearest ZO clinic.

Mineral SPF – The Best Way to Protect Post-Procedure Skin

You should be wearing SPF every day, rain or shine. However, sun protection becomes especially important after undergoing an abrasive cosmetic procedure.

Chemical peels, laser treatments and micromodelling can be a great addition to your skincare routine to address texture concerns, persistent  pigmentation and deep wrinkles. But it’s important to keep in mind that these treatments leave your complexion raw and vulnerable to UV damage. Failing to apply proper SPF protection to vulnerable, post-procedure skin can not only erase all the benefits from your treatment but cause complications such as discolouration and inflammation.

Mineral vs Chemical Protection

Your skin is sensitised and vulnerable after a procedure, so you need to be cautious of harsh ingredients in your skincare that can further irritate the skin or slow down the healing process. The most common chemical SPF filters – benzophenone, oxybenzone and octocrylene, have been associated with irritation and photoallergic contact dermatitis reactions.

microneedling, post-procedure skin protection

This is why it’s better to opt for mineral-based sun protection in the first few weeks after your procedure. Mineral SPF acts like a physical shield that sits on top of your skin rather than being absorbed deep into its layers. Mineral formulas are gentler and easier to tolerate by vulnerable, sensitised skin. Powder formats are especially suitable for post-procedure use, since application doesn’t require rubbing or tugging of the skin.

The most common ingredients in mineral SPF products– zinc oxide and titanium dioxide offer benefits beyond UV protection. Zinc oxide has proven antimicrobial properties that soothe stinging irritation and help wound healing. If you are prone to rosacea and eczema flare-ups, titanium dioxide is a safe option for you.

The ZO Difference

Our new Sunscreen + Powder SPF 30 is the latest addition to the Triple Protection range that brings exclusive antioxidant technology and superior skin defence.

zo skin health sunscreen+powder spf 30

The mineral-based formula offers gentle and safe SPF protection for raw, post- procedure skin. It comes in a brush, densely packed with ultra-soft bristles, to ensure the powder is evenly applied on your skin. Colour pigments and light reflecting minerals make it easy to blend into all skin tones and avoid the dreaded ashy residue associated with most minerals SPFs.

Sunscreen + Powder SPF 30 is enriched with jojoba butter and seed sil that enable lipid replenishment and help skin barrier restoration. Fractionated melanin protects against blue (HEV) light, while a slow-release ZOX12® complex combats free radical damage and IR-A rays.

To ensure optimal protection, reapply every two hours.

Introducing ZO Skin Health Sunscreen + Powder SPF 30

Since the early 1990s, skin cancer incidence rates have more than doubled (135%) in the UK. There are around 16,200 new cases every year, which makes it the 5th most common cancer in the UK.

86% of melanoma skin cancers are associated with exposure to risk factors and could be prevented. ZO Skin Health has launched the latest addition to its sun protection range – ZO Skin Health Sunscreen + Powder SPF 30, to make SPF reapplication easy and help patients stay protected at all times.

The ZO® Difference

ZO® Triple-Protection products are formulated with exclusive technologies and the highest quality ingredients to offer superior protection against UV rays and environmental aggressors.

zo skin health triple sperctrum protection

Sunscreen + Powder SPF 30 formula features titanium dioxide and zinc oxide to offer physical protection from UVB and UVA rays. The formula is enriched with vitamins A, C and E to protect the skin from infrared damage and free radicals. Rosemary and beta-glucan extracts counteract dullness and dehydration, caused by air pollution, while fractured melanin protects against the HEV light, emitted from phones and computer screens.

Easy and Convenient Reapplication

zo skin health sunscreen+powder spf 30

The new Sunscreen + Powder SPF 30 comes in a compact brush format to offer on-the-go sunscreen reapplication. The brush is densely packed with ultra-soft bristles to guarantee even application onto the skin. Most importantly, the brush doesn’t shed and cleans easily, ensuring it will continue to provide smooth and consistent application over time.

The Perfect Companion for Every Skin Tone

zo skin health sunscreen + powder spf 30

Sunscreen + Powder SPF 30 comes in three universal shades – light, medium, and deep. Light has a cool undertone which neutralises the signs of redness and irritation. Medium creates a clean, even canvas for a natural look or sheer base, while deep is perfect for adding warmth and definition for a bronzed look. The powder is formulated with advanced colour-enhancing pigments to provide buildable coverage and a touch of luminosity for instant complexion perfection.

ZO Skin Health Firming Serum – Defying the Mechanism of Skin Ageing

Formulated with an exclusive biomimetric complex and anti-inflammatory system, ZO Skin Health Firming Serum reduces the appearance of sagging and skin laxity for a more defined facial contour.

The mechanism of skin ageing

The process of skin ageing is complex and influenced by a myriad of intrinsic and extrinsic factors. The most prominent intrinsic biological processes involved in skin ageing are alterations in DNA repair and stability, mitochondrial function and cellular metabolism. Extrinsic factors such as UV radiation and free radical damage cause morphological alterations in the dermis, alter fibroblast activity and, ultimately, lead to a thinner epidermis, loss of collagen and weakened skin repair.

Over time, the loss of structural proteins collagen and elastin impact skin’s ability to maintain its shape and structural integrity. Unable to withstand mechanical shocks and environmental stressors, the epidermis slackens, collapses and loses its defined shape.

The Solution

Firming Serum’s bioactive formula supports the anchoring fibrils that connect the dermis to the epidermis and maintains the structural integrity of the skin.

Sodium DNA

Fibroblast cells in ageing skin become inactive and unable to restore collagen and elastin. Sodium DNA works alongside skin’s matrix formation process to support fibroblast activity and improve elasticity and firmness.

ZCORE Anti-Inflammatory Complex

Fibrillar degeneration weakens the dermal-epidermal junction and results in inadequate nutrient replenishment between the dermis and the epidermis. ZCORE complex features biomimetric tetrapeptide and sweet yellow clover to support the anchoring fibrils for dermal-epidermal junction integrity.

Clinically Proven Results

In a comprehensive clinical study of 45 participants, Firming Serum has been proven to improve the appearance of firmness, sagging and help maintain skin’s shape and strength.

97% of participants showed significant improvement in firmness by week 12 as measured by Cutometer, 88% demonstrated elasticity improvement while 93% of subjects showed significant improvement in mid-face and jawline sagging by week 12 measured by an expert clinical grader.

Comprehensive Solutions

Targeted treatment of laxity and sagging cannot replace the basics steps of a healthy routine – cleanse, exfoliation, UV and antioxidant protection. Firming Serum’s lightweight formula is mild enough to be tolerated by all skin types and suitable for sensitive skin areas. It can, therefore, be added to all anti-ageing programmes. Firming Serum is applied AM and PM after GSR and Daily Power Defense and before high molecular weight products such as Growth Factor Serum.



ZO Skin Health Wrinkle + Texture Repair – New, Improved Formula

ZO Skin Health’s comprehensive anti-ageing solution has been reformulated to increase efficacy and accelerate treatment results.Beneath the surface, the first manifestation of skin ageing begins with the degradation of skin’s collagen network.

Wrinkle + Texture Repair targets the underlying pathophysiology of skin ageing and stimulates the restoration of collagen-1, fibronectin and hyaluronic acid aids in skin’s collagen network. The formula features a blend of retinol, carprooyl tetrapeptide-3, melilotus officinalis extract, Buddleja davidii meristem cell culture and phospholipids that work synergistically to restore natural hydration and minimise the appearance of wrinkles and all signs of ageing.

zo skin health wrinkle + texture repair

Advanced Delivery System

The key to Wrinkle +Texture Repair lies efficacy in its new delivery system. ZO Skin Health has introduced a microemulsion delivery system that enables the rapid release of retinol and accelerated penetration in the deeper skin layers.

Clinically Proven Results

  • The Study

A 12-week clinical study, including 43 subjects was conducted to evaluate the effect of Wrinkle + Texture Repair formula on the facial skin of female subjects.

All subjects were initially analysed at baseline, and then reassessed at 2, 4, 8, and 12 weeks of product use. Skin changes in all subjects were analysed by an external grader, utilising a visual scale to measure lines, wrinkles and changes in skin texture.

Bio-instrumental analyses were also conducted utilising Tewameter to assess trans-epidermal water loss and digital images were obtained with a Clarity 2D system at all study timepoints, and analysed by a trained technician. All data points were compared against baseline visit results.

  • The Results

After 12 weeks of application, a significant improvement in all expert graded skin attributes was found, and no significant adverse events were reported during the study. Participants were overwhelmingly satisfied with the results, with 93% of participants showing improvement by the end of the study. 98% of participants showed improvements in crow’s feet and facial fine lines by week 12, and 95% of participants showed improvements in skin function by week 12.

Furthermore, none of the expert graded results showed any plateauing effect at the conclusion of the study, which suggests that patients may expect to see even further benefits when using the product for longer than 12 weeks.

The Perfect Skincare Routine for Dry & Dehydrated Skin

Dry, flaky  and  dehydrated skin and cold weather go hand in hand. This is because low temperatures mean low humidity, both outdoors and indoors. The water content of the epidermis tends to reflect the level of humidity around it, so even oily and combination skin types suffer from red, itchy skin during winter months.

Fortunately, few simple changes in your daily skincare routine can alleviate winter skin symptoms.

Gentle Exfoliation

dehydrated skin gentle cleanser

Switching abrasive physical exfoliators for a gentle cleanser can help the skin adjust to cooler, drier weather. ZO Gentle Cleanser For All Skin Types is great for dehydrated skin thanks to a potent blend of antioxidants and botanical extracts that removes dead cells, sebum and dirt, while maintaining healthy lipid balance and helps retain epidermis natural moisture level.

Switch to a Non-Retinol Serum

Retinol is a gold standard ingredient for treating all signs of skin ageing and inflammatory conditions such as acne and rosacea. However, skin becomes drier and more prone to irritation during winter months, so cutting down the frequency of application or switching to an antioxidant serum is beneficial for drier skin types.

dehydrated skin growth factor serum

ZO Skin Health Growth Factor Serum is a retinol-free formulation that delivers daily DNA repair and antioxidant protection to slow and correct the signs of ageing. Formulated with ZPRO™ exclusive antioxidant biomimetic protein complex, Growth Factor Serum stimulates the production of collagen and hyaluronic acid and protect skin cells DNA from future damage.

Enzymes are Key

Sloughing off dry patches with exfoliating brushes and other mechanical devices is a short-term fix that can exacerbate dry skin symptoms and lead to more irritation and flaking.


Ceramides are enzymes, found naturally in the uppermost layers of the skin, that help shed dead cells and limit moisture loss. ZO Skin Health Renewal Crème features ceramides, antioxidants and jojoba esters to reinforce skin barrier functions and restore healthy hydration levels.

Don’t Skip On SPF Protection

During winter months, sunlight contains less UVB radiation which is the culprit for sun burns. However, long-wavelength UVA rays are present all year can penetrate through clouds, fog and window glass, causing oxidative stress and premature signs of ageing. SPF protection of minimum 30 is vital in high altitudes as snow reflects 80% of UV rays, in comparison to sand and water that only reflect around 10-15%.

dehydrated skin smart tone spf 50

ZO Skin Health Smart Tone SPF 50 blends seamlessly into all skin types and provides an invisible, matte protection against UVB, UVA, blue light and air pollution.